1. The method sets the tone -- 2. Preclinical studies design and place of rodents -- 3. Preclinical studies design and place of rabbits -- 4. Preclinical studies design and place of swine -- 5. Preclinical studies in the canine model -- 6. Preclinical studies design and place of caprine and ovine -- 7. Clinical investigations in implant dentistry:experimentation versus observation and the future of merging data -- 8. Translational aspects in living mammalian organisms -- 9. Biomechanics of the radicular component of endosteal implants -- 10. Radiographic imaging in implant dentistry -- 11. Biological events at the interface between the radicular part of the implant and bone -- 12. Mechanics of the implant-abutment-connection -- 13. Mechanics of the prosthetic rehabilitations -- 14. Imaging of non resorbable bone substitutes -- 15. Biology of low-substitution bone substitutes -- 16. Imaging of resorbable bone substitutes -- 17. Biology of resorbable bone substitutes -- 18. Membranes and soft tissues enhancers -- 19. Biomarkers for implant dentistry studies -- 20. Computer-Assisted Implant Dentistry -- 21. Insight into statistical procedure.