The history of the Loa loa parasite, its biology and experimental models -- Epidemiology and Public health importance -- The role of human host and parasite genetics in the outcome of loiasis -- Loiasis disease typical and atypical clinical manifestations, burden and local aspects of the disease -- Clinical aspects: Treatment of simple and complicated forms of loiasis -- Diagnosis of Loa loa: from blood identification to innovative approaches -- Immune mechanism in loiasis and interactions with other infections -- The Loa loa genome and potential immunological and therapeutic molecular targets with medicinal plants.