Mimicking pancreas development with human pluripotent stem cells -- Pancreatic cell fate specification: insights into developmental mechanisms and their application for lineage reprogramming -- The evolution of methods for in vitro differentiation of stem cell derived islets -- Signaling pathways that govern the formation, expansion and maturation of pancreatic progenitors -- Building islets from the ground up using stem cells -- Pancreatic progenitor proliferation -- Selecting biocompatible biomaterials for stem cell derived islet transplantation -- Scaffolds for encapsulation of stem-cell-derived β cells -- 3d printing of new islets -- Biological scaffolds and hydrogels in islet organoids -- 3-D organoids of mesenchymal stromal and pancreatic islet cells -- Bioengineered insulin producing endocrine tissues -- Bioactive materials for cell encapsulation -- Strategies to boost islet graft oxygenation -- Vascularizing device strategies -- Immunogenicity of stem cell derived islets -- Immune evasive stemcell islets -- Encapsulation of stem cell-derived islets: recent progress -- Islet immunoengineering -- Stem cell genome editing tools -- Selection of SC-derived pancreatic progenitors and β cell -- Considerations pertaining to implant sites for cell-based insulin replacement -- Safety switches in pluripotent stem cells -- Safety: teratoma risk -- Stem cell derived islets transplantation in non-human primates -- Social / Legal / Ethical issues pertaining to use of pluripotent stem cells -- Cost-effectiveness considerations for stem cell derived islet replacement therapy -- Lessons from clinical trials of islet cell replacement -- Scale up and Biomanufacturing of Stem Cell- derived Islets -- Minimal SC-β cell properties for transplantation in diabetic patients -- Autologous stem cell islets for patients with chronic pancreatitis and diabetes -- Clinical Trials -- Modeling monogenic diabetes with stem cells -- Stem and progenitor cells in pancreas development, regeneration and drug screening. .