Introduction -- Challenges of High-Speed System Design -- Understanding AC and DC Input/Output Signals -- Practical Analog Filter Design -- Transmission Line (TL) Effects -- S-Parameters -- Effects of Crosstalk -- Power Supply Design Considerations -- Power Supply Decoupling -- Phase-Locked Loop (PLL) -- Data Converter Overview -- Printed Circuit Board (PCB) -- Electromagnetic Interference (EMI) -- Memory Sub-System Design Considerations -- Conclusion.