Part I. Basic Science -- 1: Animal models based on immune challenge: the links to brain changes and psychiatric disorders -- 2: The prenatal immune activation model for schizophrenia and the role of stress in puberty -- 3: Rodent models of stress induced depression: the link between stress and immune system related changes -- 4. Experimental Human Endotoxemia, Sickness Behavior and Neuropsychiatric Diseases -- Part II. Translational Medicine -- 5. Mild encephalitis theory of psychiatric disorders -- 6. The role of Infection and autoimmune disorders for schizophrenia and depression: Consequences from a large-scale epidemiological study -- 7. Exposure to microorganisms and adult psychiatric disorders: proofs for causal relationship -- 8. Depression: From activation of immune-inflammatory pathways to oxidative-stress-induced autoimmune responses and neuroprogression -- 9. Immune system related markers changes in childhood neuropsychiatric disorders: cause and consequence -- 10. Cytokines and related metabolic biomarkers in adult neuropsychiatric disorders: possible roles in clinical application -- 11. Immune system changes play a role in the development of the metabolic syndrome in psychiatric disorders -- 12. The activation of microglia in severe neuropsychiatric disorders: Focus on infectious mechanisms and PET imaging -- 13. The role of inflammation in Tourette's Syndrome -- 14. The role of inflammation in Autism -- 15. The role of inflammation in Alzheimer's Disease -- Part III: Therapeutic application -- 16. Antidepressants: influence on immune system related parameters -- 17. Cyclooxygenase-2 inhibition in management of depression and schizophrenia -- 18. Poly-unsaturated fatty-acids in management of adult psychiatric disorders.