Part 1: Oxidative Stress: Basic Principles in the Liver Scenario -- Principles of Redox Signaling -- Oxidative Stress, Antioxidant Defenses and the Liver -- Oxidative Mechanisms in Liver Senescence and Regeneration -- Part 2: Oxidative Stress and Liver Pathophysiology: From Cell Damage and Death to Inflammatory and Fibrogenic Responses -- Oxidative Stress and Hepatocellular Injury -- Oxidative Stress and the Unfolded Protein Response in the Liver -- Oxidative Stress and Liver Inflammation -- Oxidative Stress and Liver Ischemia-Reperfusion Injury -- Oxidative Stress and Liver Fibrogenesis -- Part 3: Oxidative Stress in Specific Liver Disease Conditions -- Oxidative Stress in Acute Liver Failure -- Oxidative Stress in Alcoholic Liver Disease -- Oxidative Stress in Chronic Viral Hepatitis -- Oxidative Stress in Nonalcoholic Fatty Liver Disease -- Oxidative Stress in Non-autoimmune Biliary Diseases -- Oxidative Stress in Autoimmune Liver Diseases -- Oxidative Stress and Hepatic Iron Overload -- Oxidative Stress in the Central Nervous System Complications of Chronic Liver Failure -- Oxidative Stress and Liver Transplantation -- Antioxidant Approach to the Therapy of Chronic Liver Disease -- Part 4: Oxidative Stress and Liver Cancer -- Liver Cancer Classification -- Oxidative Stress Mechanisms in Hepatocarcinogenesis -- The Role of Oxidative Stress in Hepatocarcinogenesis.