Metabolic Remodeling in Bioenergetic Disorders and Cancer -- Tumor Cell Complexity and Metabolic Flexibility -- Autophagy and Tumor Cell Metabolism.-Tumour Hypoxia and the Hypoxia-Inducible Transcription -- MYC Regulation of Metabolism and Cancer -- Pyruvate Kinase M2: A Metabolic Tuner -- Role of the Pentose Phosphate Pathway in Tumour Metabolism -- Enzymes of the Tumour Metabolome in Diagnostic Applications -- Contribution of pH Alterations to the Tumor Microenvironment -- Mitochondrial Mutations in Cancer Progression: Causative, Bystanders, or Modifiers of Tumorigenesis? The Relevance of the Mitochondrial H+-ATP Synthase -- Canceromics Studies Unravel Tumor's Glutamine Addiction -- Essential Role of Mitochondria in Pyrimidine Metabolism -- Metabolic Fluxes in Cancer Metabolism -- Targeted 13C-Labeled Tracer Fate Associations for Drug Efficacy Testing in Cancer.