1. Improving research on biomarkers for early detection and screening of cancers / Claire S. Zhu, Paul F. Pinsky and Christine D. Berg -- 2. Biomarkers of oxidative stress in carcinogenesis / Humberto Rodriguez-Rocha, Aracely Garcia-Garcia and Rodrigo Franco -- 3. [beta]-catenin : a novel biomarker and therapeutic target in liver cancer / Anupam Bishayee -- 4. Urine biomarkers for prostate cancer detection / Yan-Hua Chen, Art A. Rodriguez and Qun Lu -- 5. Ectodomain shedding as a mechanism to generate cancer biomarkers (ectomarkers) / Maria J. Ruiz-Echevarria, Xiaofei Chen and Ryan F. Overcash -- 6. The BRCT signaling landscape : emerging concepts and implications in tumorigenesis and cancer diagnostics / Dimitris Mastellos and George Nounesis -- 7. Cellular senescence and cancer development : antagonistic and synergistic relations / Dimitris Kletsas -- 8. MicroRNAs : from regulators of gene expression to cancer biomarkers / Stamatina Giannouli. [et al.] -- 9. Targeting PARP-1 in breast cancer : the paradigm of a DNA repair-based therapeutic strategy / Francisco Javier Oliver. [et al.] -- 10. Statins in prostate cancer : prevention and treatment / Khaled Aziz and Phuoc T. Tran -- 11. Mechanistic aspects of oxidative stress involvement in human environmental and occupational carcinogenesis / Dominique Ziech, Aglaia Pappa and Mihalis I. Panayiotidis.