chapter 1 Principles of Developmental Toxicology Revisited -- chapter 2 Experimental Approaches to Evaluate Mechanisms of Developmental Toxicity -- chapter 3 Pathogenesis of Abnormal Development -- chapter 4 Maternally Mediated Effects on Development -- chapter 5 Paternally Mediated Effects on Development -- chapter 6 Comparative Features of Vertebrate Embryology -- chapter 7 Developmental Toxicity Testing — Methodology -- chapter 8 Nonclinical Juvenile Toxicity Testing -- chapter 9 Significance, Reliability, and Interpretation of Developmental and Reproductive Toxicity Study Findings -- chapter 10 Testing for Reproductive Toxicity -- chapter 11 The U.S. EPA Endocrine Disruptor Screening Program: In Vitro and In Vivo Mammalian Tier I Screening Assays -- chapter 12 Role of Xenobiotic Metabolism in Developmental and Reproductive Toxicity -- chapter 13 Use of Toxicokinetics in Developmental and Reproductive Toxicology -- chapter 14 Cellular, Biochemical, and Molecular Techniques in Developmental Toxicology -- chapter 15 Functional Genomics and Proteomics in Developmental and Reproductive Toxicology -- chapter 16 In Vitro Methods for the Study of Mechanisms of Developmental Toxicology -- chapter 17 Statistical Analysis for Developmental and Reproductive Toxicologists -- chapter 18 Quality Concerns for Developmental and Reproductive Toxicologists -- chapter 19 Perspectives on the Developmental and Reproductive Toxicity Guidelines -- chapter 20 Human Studies — Epidemiologic Techniques in Developmental and Reproductive Toxicology -- chapter 21 Developmental and Reproductive Toxicity Risk Assessment for Environmental Agents -- chapter 22 Principles of Risk Assessment — FDA Perspective.