Origin and nature of chronic lymphocytic leukemia B cells / Nicolas Chiorazzi and Manlio Ferrarini -- Gene expression profiling in the study of CLL / Ulf Klein -- Molecular pathogenesis / Arianna Bottoni, Carlo M. Croce, and George A. Calin -- Chronic lymphocytic leukemia and the B cell receptor / Marta Muzio and Federico Caligaris-Cappio -- Etiology of CLL : the role of MBL / Paolo Ghia and Andrew C. Rawstron -- Apoptosis dysregulation in CLL / Victoria Del Gaizo Moore and Anthony Letai -- Differential diagnosis, staging, and prognostic factors / Thorsten Zenz, Hartmut Dohner, and Stephan Stilgenbauer -- Frontline therapy of chronic lymphocytic leukemia / Barbara Eichhorst and Michael Hallek -- Treatment of patients with relapsed or refractory chronic lymphocytic leukemia / Karen W.L. Yee, Michael J. Keating, and Susan M. O'Brien -- New therapies in chronic lymphocytic leukemia / John C. Byrd. [et al.] -- Stem cell transplantation in CLL / John G. Gribben -- Gene therapy, vaccines, and immune modulation / William G. Wierda -- Profilymphocytic leukemias / Claire E. Dearden -- CLL specific complications : autoimmunity and Richter's transformation / Dennis A. Carney and John F. Seymour -- Infectious complications in patients with chronic lymphocytic leukemia / Elias Anaissie.