1. The molecular pathogenesis and pathophysiology of prostate cancer / William G. Nelson and Angelo M. De Marzo -- 2. Targeted therapies for cancer : definitions and attributes / Edward A. Sausville -- 3. Novel biomarkers for disease diagnosis, prognosis, and prediction / James V. Tricoli -- 4. The endothelin pathway and its modulation in prostate cancer / Antonio Jimeno and Michael Carducci -- 5. Targeting extracellular molecules in prostate cancer--mechanisms to inhibit entry into the cell-signaling abyss / Susan F. Slovin -- 6. Immunologic approaches to prostate cancer / Lawrence Fong and Eric J. Small -- 7. Gene therapy and novel clinical trial design / Henry T. Tsai and Jonathan W. Simons -- 8. Angiogenesis inhibitors in prostate cancer / William D. Figg. [et al.] -- 9. What antisense oligonucleotides have promise in prostate cancer / Kim N. Chi and Martin E. Gleave -- 10. Novel approaches to androgen receptor blockade / Ingo K. Mellinghoff -- 11. Can post-transcription modifiers change the course of prostate cancer? / David Z. Qian and Roberto Pili -- 12. Telomere targeting agents / Angelika M. Burger and Lloyd R. Kelland -- 13. Expanding the role of EGFR inhibitors in prostate cancer / Srikala S. Sridhar and Malcolm J. Moore -- 14. Bone-directed therapy in prostate cancer : rationale and novel approaches / Colby L. Eaton, Kate D. Linton, and Freddie C. Hamdy -- 15. Inhibiting the proteasome in advanced prostate cancer / Robert Dreicer -- 16. Hsp90 : a target for prostate cancer therapy / David B. Solit, Howard I. Scher, and Neal Rosen -- 17. Vitamin D analogs and their role in prostate cancer / Tomasz M. Beer and Anne Myrthue -- 18. Other novel therapies / Arif Hussain and Richard Schraeder --

19. Molecular imaging, clinical trial design, and the development of emerging therapies for metastatic prostate cancer / Michael J. Morris. [et al.].