Overview of the pathogenesis of acne / Guy F. Webster -- Cell biology of the pilosebaceous unit / Helen Knaggs -- Sebum secretion and acne / Philip W. Wertz -- The molecular biology of retinoids and their receptors / Anthony V. Rawlings -- Molecular biology of peroxisome Profiliferator-activated receptors in relation to sebaceous glands and acne / Michaela M.T. Downie and Terence Kealey -- Antimicrobial peptides and acne / Michael P. Philpott -- Hormonal influences in acne / Diane Thiboutot -- Antimicrobial therapy in acne / Guy F. Webster -- Topical retinoids / Daniela Kroshinsky and Alan R. Shalita -- Phototherapy and laser therapy of acne / Guy F. Webster -- Benzoyl peroxide and salicylic acid therapy / Gabi Gross -- Treating acne with octadecenedioic acid: mechanism of action, skin delivery, and clinical results / Johann W. Wiechers. [et al.] -- The effect of sphingolipids as a new therapeutic option for acne treatment / Saskia K. Klee, Mike Farwick, and Peter Lersch -- 5[alpha]-reductase and its inhibitors / Rainer Voegeli. [et al.] -- Sebum : physical-chemical properties, macromolecular structure, and effects of ingredients / Linda D. Rhein, Joel L. Zatz, and Monica R. Motwani -- Targeted delivery of actives from topical treatment products to the pilosebaceous unit / Linda D. Rhein, Joel L. Zatz, and Monica R. Motwani -- Topical therapy and formulation principles / Steve Boothroyd -- In vitro models for the evaluation of anti-acne technologies / John Bajor.