1. Copper and copper alloys / Harold T. Michels -- 2. Corrosion chemistry of copper : formation of potentially skin-diffusible compounds / Jurij J. Hostynek -- 3. Basics of metal skin penetration : scope and limitations / Jurij J. Hostynek and Howard I. Maibach -- 4. Percutaneous absorption of copper compounds / Jurij J. Hostynek and Howard I. Maibach -- 5. Diffusion of copper through human skin in vivo / Jurij J. Hostynek, Howard I. Maibach, and Frank Dreher -- 6. Irritation potential of copper compounds / Jurij J. Hostynek and Howard I. Maibach -- 7. Copper hypersensitivity : dermatologic aspects : overview / Jurij J. Hostynek and Howard I. Maibach -- 8. Copper in medicine and personal care : a historical overview / Roberto Milanino -- 9. The role of copper in onset, development, and control of acute and chronic inflammation / Roberto Milanino -- 10. Copper jewelry and arthritis / Brenda J. Harrison -- 11. Role of copper in anti-inflammatory therapy and the potential for its transdermal application / Jurij J. Hostynek and Roberto Milanino.