part Part I Pathophysiology of Obesity -- chapter 1 Energy Homeostasis / chapter 2 The Pathophysiology of Appetite Control / chapter 3 Genetics of Obesity / chapter 4 Antipsychotic Drugs, Weight Gain, and Diabetes / part Part II General Therapeutic Aspects -- chapter 5 Obesity and Associated Complications / chapter 6 Psychosocial Aspects of Obesity / chapter 7 Basic Considerations and Guidelines for Treatment / part Part III Benefits of Weight Loss -- chapter 8 Weight Loss and Cardiovascular Risk Factors / chapter 9 Weight Loss and Associated Diseases / chapter 10 Weight Loss and Metabolic Diseases / part Part IV Drugs on the Market -- chapter 11 Orlistat / chapter 12 Sibutramine / chapter 13 Noradrenergic, Serotonergic, Antiepileptic, and Herbal Drugs / chapter 14 Adverse Effects and Drug-Drug Interactions / part Part V Drugs in Research and Development -- chapter 15 Central Targets for Antiobesity Drugs / chapter 16 Leptin and Other Appetite Suppressants / chapter 17 Peripheral Targets for Antiobesity Drugs / chapter 18 Targeting Thermogenesis in the Development of Antiobesity Drugs / part Part VI Treatment Alternatives -- chapter 19 Diet, Physical Activity, and Behavior / chapter 20 Dietary Supplements and Herbal Preparations / chapter 21 Surgical Treatment of Obesity / chapter 22 Efficacy of Different Antiobesity Interventions / chapter 23 Integrated Approach to Treatment and Prevention