1. Anatomy of the mitral valvular complex / Nicolas M. Van Mieghem, Jackie S. McGhie, and Margot M. Bartelings -- 2. The pathophysiology of mitral regurgitation / Blase A. Carabello -- 3. Genesis of the surgical edge-to-edge repair / Ottavio Alfieri and Michele De Bonis -- 4. Outcomes from surgical edge-to-edge repair / Francesco Maisano -- 5. An overview of the literature on surgical mitral valve repair / Sophie Jones, Michael Argenziano, and Allan Schwartz -- 6. Development of percutaneous edge-to-edge repair : the MitraClip story / Frederick St. Goar -- 7. MitraClip system design and history of development / Troy Thornton and Liz McDermott -- 8. The EVEREST trial results / Alice Perlowski and Ted Feldman -- 9. Outcomes for functional mitral regurgitation / James Hermiller, Douglas Segar, David Heimansohn, and Nauman Siddiqi -- 10. The role of percutaneous mitral repair for high risk patients / Willis Wu and Patrick Whitlow -- 11. Echocardiographic evaluation for mitral regurgitation grading and patient selection / Ehrin J. Armstrong and Elyse Foster -- 12. Understanding the limits of patient selection for edge-to-edge repair / Ehrin J. Armstrong and Jason H. Rogers -- 13. The basic technique for the Evalve MitraClip procedure / Gretchen Gary and Ted Feldman -- 14. Procedural tips and tricks / Saibal Kar and Wen-Loong Yeow -- 15. Training and simulation / Scott Lim -- 16. Special techniques for functional mitral regurgitation / Olaf Franzen, Stephan von Bardeleben, and Susanna Price -- 17. The European experience since CE approval / Corrado Tamborino, Gian Paolo Ussia, and Valeria Cammalleri --

18. An interventionalist's approach to the practical use of TEE guidance / Howard C. Herrmann -- 19. Echocardiographic guidance of MitraClip mitral valve repair / Frank E. Silvestry -- 20. A critical appraisal of edge-to-edge repair with the MitraClip / Peter C. Block -- 21. Technique for surgical removal of the MitraClip / Lori Soni and Michael Argenziano -- 22. Special considerations for mitral valve repair after clip therapy / Subhasis Chatterjee, David A. Heimansohn, and John C. Alexander -- 23. Gross and histologic findings after MitraClip placement / Elena Ladich, Masataka Nakano, and Renu Virmani -- 24. Future directions in percutaneous mitral therapy / Ted Feldman and Frederick St. Goar.