chapter 1 The Endothelium as an Organ / chapter 2 Blood-Brain Barrier / chapter 3 Lymphatic Endothelium / chapter 4 High Endothelial Venules / chapter 5 The Use of Proteomics to Map Phenotypic Heterogeneity of the Endothelium / chapter 6 The Use of Genomics to Map Phenotypic Heterogeneity of the Endothelium -- chapter 7 The Role of Genetic Predeterminants in Regulating the Phenotypic Heterogeneity of the Endothelium / chapter 8 The Use of Fate Mapping Studies to Follow Lineage Determination of the Endothelium / chapter 9 Oxygen Regulation of Endothelial Cell Phenotypes / chapter 10 Fluid Mechanical Forces as Extrinsic Modifiers of Endothelial Function -- chapter 11 Vascular Bed-Specific Signaling and Angiogenesis / chapter 12 Differential Regulation of Endothelial Cell Barrier Function / chapter 13 Differential Regulation of Leukocyte-Endothelial Cell Interactions / chapter 14 Vascular Biology of the Placenta / chapter 15 Blood Endothelial Cells / chapter 16 Determination of Endothelial Heterogeneity by the Recruitment of Bone Marrow Derived Endothelial Progenitors / chapter 17 Transcriptional Networks and Endothelial Lineage -- chapter 18 The Diversity of Vascular Disease: A Clinician's Perspective / chapter 19 Molecular Targets of Tumor Vasculature / chapter 20 The Role of the Endothelium in Severe Sepsis and Multiple Organ Dysfunction / chapter 21 The Hepatic Sinusoidal Endothelial Cell as a Primary Target of Disease / chapter 22 Endothelium and Hemostasis / chapter 23 Thrombotic Microangiopathies: Role of Microvascular Endothelium in Pathogenesis / chapter 24 Pulmonary Circulation and Pulmonary Hypertension / chapter 25 Endothelial Cell Phenotypes Associated with Organ Transplantation