ch. 1. Overview of protein conjugation -- ch. 2. Review of protein and nucleic acid chemistry -- ch. 3. Reagents targeted to specific functional groups -- ch. 4. How to design and choose cross-linking reagents -- ch. 5. Homobifunctional cross-linking reagents -- ch. 6. Heterobifunctional cross-linkers -- ch. 7. Multifunctional cross-linking reagents -- ch. 8. Monofunctional and zero-length cross-linking reagents -- ch. 9. General approaches for chemical cross-linking -- ch. 10. Analysis of cross-linked products -- ch. 11. Applications of chemical cross-linking to the study of biological macromolecules -- ch. 12. Applications of chemical conjugation in the preparation of immunoconjugates and immunogens -- ch. 13. Application of chemical conjugation for the preparation of immunotoxins and other drug conjugates for targeting theraputics -- ch. 14. Application of chemical conjugation to solid-state chemistry.