1. Introduction and historical development / Dale A. Seiberling -- 2. Project planning for the CIPable pharmaceutical or biopharmaceutical facility / Johannes R. Roebers and Dale A. Seiberling -- 3. Water for the CIP system / Jay C. Ankers -- 4. The composition of cleaning agents for the pharmaceutical industries / Dietmar Rosner -- 5. Cleaning Cycle Sequences / Sally J. Rush -- 6. CIP system components and configurations / Dale A. Seiberling -- 7. CIP system instrumentation and controls / Barry J. Andersen -- 8. Cleaning agent injection systems / Samuel F. Lebowitz -- 9. CIP spray device design and application / John W. Franks and Dale A. Seiberling -- 10. CIP distribution piping systems / Samuel F. Lebowitz -- 11. Materials of construction and surface finishes / David M. Greene -- 12. Cleanable in-line components / Lyle W. Clem -- 13. Cleanable liquids processing equipment and systems / Dale A. Seiberling -- 14. Cleanable solids processing equipment and systems / Simon E.J. Forder -- 15. Cleanable API processing equipment and systems / Gerald J. Cerulli -- 16. CIP system troubleshooting guide / Sally J. Rush -- 17. Waste treatment for the CIP system / Linda Rauch and Jay C. Ankers -- 18. Commissioning and qualification / James P. Norton -- 19. Cleaning validation strategies / Charles Lankford -- 20. International regulations / Albrecht Killinger and Joachim Holler.