chapter 1 Assay Development for Protein Kinases and Phosphatases -- chapter 2 Fluorescence-Based Biochemical Protease Assay Formats -- chapter 3 Assay Development for Nuclear Hormone Receptors -- chapter 4 Assay Development for G Protein-Coupled Receptors and Ion Channels -- chapter 5 Assay Development for Heat Shock Proteins -- chapter 6 Assay Development for Cell Viability and Apoptosis for High-Throughput Screening -- chapter 7 Assay Development for Antimicrobial Drug Discovery -- chapter 8 Image-Based High Content Screening -- chapter 9 Application of RNA Interference in Drug Discovery -- chapter 10 Assay Development Using Primary and Primary-Like Cells -- chapter 11 Screening Automation -- chapter 12 Compound Library Management -- chapter 13 Unique Discovery Aspects of Utilizing Botanical Sources -- chapter 14 Screening Informatics.