part SECTION 1 Fundamentals of Expression Profiling Analysis -- chapter 1 Preparation and Utilization of Microarrays / chapter 2 Comparative Studies Using cDNA vs. Oligonucleotide Arrays / chapter 3 Quality Control of Expression Profiling Data / chapter 4 An Introduction to Cluster Analysis / part Section 2 Expression Profiling and Toxicology: The Advent of Toxicogenomics -- chapter 5 Transcriptional Profiling in Toxicology / part Section 3 Model Systems in Toxicogenomic Studies -- chapter 6 Microarrays in Drug Metabolism and Toxicology: Rat Liver Responses to Prototypical CYP Inducers / chapter 7 Characterization of Hepatocytes and Their Use as a Model System in Toxicogenomics / part Section 4 Mechanistic Toxicogenomics -- chapter 8 Molecular Signatures of Dioxin Toxicity / chapter 9 Toxicogenomic Dissection of the Antioxidant Response / chapter 10 An Overview of Mechanistic Toxicogenomic Studies / part Section 5 Predictive Toxicogenomics -- chapter 11 Gene Expression Profile Databases in Toxicity Testing / chapter 12 Predictive Toxicogenomics / chapter 13 Unsupervised Hierarchical Clustering of Toxicants / chapter 14 Toxicogenomic Analysis in Clinical Pharmacogenomic Studies / part Section 6 The Future of Toxicogenomics -- chapter 15 The Future of Toxicogenomics