pt. 1. Introduction -- pt. 2. Background -- pt. 3. Environments and prediction tools -- pt. 4. Semiconductor device technologies for extreme environments -- pt. 5. Modeling for extreme environment electronic design -- pt. 6. Device and circuit reliability in extreme environments -- pt. 7. Circuit design for extreme environments -- pt. 8. Examples of extreme environment circuit designs -- pt. 9. Verification of analog and mixed-signal systems -- pt. 10. Packaging for extreme environments -- pt. 11. Real-world extreme environment applications -- pt. 12. Appendices.