part Section I: Basic Concepts in Toxicology Testing -- chapter 1 Introduction to Principles of Toxicology -- chapter 2 Effects of Chemicals -- chapter 3 Toxicokinetics -- chapter 4 Risk Assessment and Regulatory Toxicology -- chapter 5 Descriptive Animal Toxicology Tests -- part Section II: Toxicology Testing In Vivo -- chapter 6 0 and Acute Toxicology Tests -- chapter 7 Subchronic and Chronic Toxicology Testing -- chapter 8 Acute Dermal and Ocular Toxicity Testing -- chapter 9 Toxicity Testing for Fertility and Reproduction -- chapter 10 Carcinogenicity and Mutagenicity Testing -- part Section III: Toxicology Testing In Vitro -- chapter 11 Introduction to In Vitro Toxicology Testing -- chapter 12 Cell Culture Methodology -- chapter 13 Cell Culture Methods for Acute Toxicology Testing -- chapter 14 Toxicokinetic Studies -- chapter 15 Mutagenicity Testing In Vitro -- chapter 16 Reproductive and Teratogenicity Studies In Vitro -- chapter 17 High Throughput Screening and Microarray Analysis -- chapter 18 Experimental Design and Statistics -- chapter 19 Standardization and Validation of Alternative Methods -- chapter 20 Applications of Alternative Models for Toxicology Testing.