chapter 1 Bayesian Methods for Cancer Phase I Clinical Trials / chapter 2 Design of Early Trials in Stem Cell Transplantation: A Hybrid Frequentist-Bayesian Approach * / chapter 3 Design and Analysis of Therapeutic Equivalence Trials / chapter 4 Adaptive Two-Stage Clinical Trials * / chapter 5 Design and Analysis of Cluster Randomization Trials / chapter 6 Design and Analysis of Clinical Trials with Multiple Endpoints* / chapter 7 Subgroups and Interactions * / chapter 8 A Class of Permutation Tests for Some Two-Sample Survival Data Problems / chapter 9 Bayesian Reporting of Clinical Trials / chapter 10 Methods Incorporating Compliance in Treatment Evaluation / chapter 11 Analysis of Longitudinal Data with Missingness* / chapter 12 Statistical Issues Emerging from Clinical Trials in HIV Infection