1. Basic definitions and concepts -- 2. Data graphics -- 3. Introduction to probability : the binomial and normal probability distributions -- 4. Choosing samples -- 5. Statistical inference : estimation and hypothesis testing -- 6. Sample size and power -- 7. Linear regression and correlation -- 8. Analysis of variance -- 9. Factorial designs -- 10. Transformations and outliers -- 11. Experimental design in clinical trials -- 12. Quality control -- 13, Validation -- 14. Computer-intensive methods -- 15. Nonparametric methods -- 16. Optimization techniques and screening designs.