chapter 1 Protein Crystallography in Structure-Based Drug Design -- chapter 2 Src Homology-2 Domains and Structure-Based, Small-Molecule Library Approaches to Drug Discovery -- chapter 3 Three-Dimensional Structure of the Inhibited Catalytic Domain of Human Stromelysin-1 by Heteronuclear NMR Spectroscopy -- chapter 4 Cannabinergics: Old and New Possibilities / chapter 5 Development of PET and SPECT Radioligands for Cannabinoid Receptors -- chapter 6 Structural and Pharmacological Aspects of Peptidomimetics -- chapter 7 Linkers and Resins for Solid-Phase Synthesis -- chapter 8 Allosteric Modulation of G-Protein-Coupled Receptors: Implications for Drug Action -- chapter 9 Protein Misfolding and Neurodegenerative Disease: Therapeutic Opportunities -- chapter 10 Uncoating and Adsorption Inhibitors of Rhinovirus Replication / chapter 11 Profiles of Prototype Antiviral Agents Interfering with the Initial Stages of HIV Infection.