Chemistries ; A brief introduction to traditional bioconjugate chemistry / [3+2]-dipolar cycloadditions in bioconjugation / Diels-Alder and inverse Diels-Alder reactions / The Staudinger ligation / Thiol-ene chemistry / Ligand-directed tosyl and acyl imidazole chemistry / Bioorthogonal labeling of cellular proteins by enzymatic and related mechanisms / Metal-mediated bioconjugation / Applications ; Protein and antibody labeling / Activity-based protein profiling / Nucleic acid labeling, ligation, and modification / Chemoselective reactions for glycan labeling / Chemoselective attachment of lipids to proteins / In vivo applications of bioorthogonal chemistries / Immobilization of biomolecular probes for arrays and assay : critical aspects of biointerfaces / Chemical ligations in the design of hydrogel materials / Nanoparticle bioconjugates : materials that benefit from chemoselective and bioorthogonal ligation chemistries / Application of engineered viral nanoparticles in materials and medicine