A source of information on CPS security and privacy theory, guiding principles, and state-of-the-art applications. Written by a team of experts at the forefront of the cyber-physical systems (CPS) revolution, this book provides an in-depth look at security and privacy, two of the most critical challenges facing both the CPS research and development community and ICT professionals. It explores, in depth, the key technical, social, and legal issues at stake, and it provides readers with the information they need to advance research and development in this exciting area. Cyber-physical systems (CPS) are engineered systems that are built from, and depend upon the seamless integration of computational algorithms and physical components. Advances in CPS will enable capability, adaptability, scalability, resiliency, safety, security, and usability far in excess of what simple embedded systems can provide. Just as the Internet revolutionized the way we interact with information, CPS technology has already begun to transform the way people interact with engineered systems. In the years ahead, smart CPS will drive innovation and competition across industry sectors, from agriculture, energy, and transportation, to architecture, healthcare, and manufacturing. This is a long-awaited review for all those concerned with the fundamental concepts and the state-of-the-art in security and privacy in CPS. This book provides comprehensive coverage of the technical issues affecting hardware and software in infrastructure components, as well as the blending of such systems with personal CPS. The contributors discuss various application domains, including energy, medicine, transportation, physical infrastructure, agriculture, smart cities, and many more. The book includes case studies and tutorials and supports university courses such as those in cybersecurity and privacy and CPS engineering and programming. A source of practical information and inspiration, this book will be of use in ongoing R&D and education at the confluence of security, privacy, and CPS.