So, you have a game-changing discovery ... Congratulations! -- Now what? Protect your intellectual property -- Are they buying what you're selling? The search phase -- Friend or foe : the tech transfer office and licensing -- Proof-of-concept centers : bridging the innovation gap -- Start-up management : you've to kiss a lot of frogs ... -- Graduate students and post-docs, start-up your career -- Incubators and accelerators, it's time to move out -- Do you believe in angels? Financing your company -- Your roadmap : avoid the potholes.