Drug Discovery Strategies for Neglected Tropical Diseases: Repurposing Knowledge, Mechanisms and Therapeutics to Increase Discovery Efficiency / David C Swinney, Michael P Pollastri -- Virus. Toward Antiviral Therapies for the Treatment of Zika Virus Infection: Lessons Learned from Dengue Virus / Sarah K Stevens*, Paul C Jordan*, Andreas Jekle, Jerome Deval -- Developing Therapeutics for Ebola Virus Disease: A Multifaceted Approach / Michael K Lo, Jessica R Spengler, Bobbie Rae Erickson, Christina F Spiropoulou -- Kinetoplastids. Designing Drugs to Target Trypanosoma cruzi, the Etiological Agent of Chagas Disease: When Chemistry needs Biology / Martine Keenan, Eric Chatelain -- Drug Discovery and Development for Human African Trypanosomiasis / Andrew Spaulding, Mitchell F Gallerstein, Lori Ferrins -- Discovery of Drugs for Leishmaniases: A Progress Report / Baljinder Singh, Frederick S Buckner, Michael P Pollastri -- Helminths. Onchocerciasis Drug Discovery / Natalie A Hawryluk, Ivan Scandale -- Drug Discovery and Development for Schistosomiasis / Conor R Caffrey, Nelly El-Sakkary, Patrick Mäder, Reimar Krieg, Katja Becker, Martin Schlitzer, David H Drewry, Jonathan L Vennerstrom, Christoph G Grevelding -- Soil-transmitted Helminthiasis -- Challenges with Discovery of Novel Anthelmintics / Graham M Kyne, Michael P Curtis, Jennifer Keiser, Debra J Woods -- Drug Discovery and Development for the Treatment of Echinococcosis, Caused by the Tapeworms Echinococcus granulosus and Echinococcus multilocularis / Andrew Hemphill, Reto Rufener, Dominic Ritler, Luca Dick, Britta Lundström-Stadelmann -- New Insights into the Treatment of Foodborne Trematode Infections / Rafael Toledo, Alba Cortés, Maria Álvarez-Izquierdo, Carla Muñoz-Antoli, J Guillermo Esteban -- Bacteria. Buruli Ulcer / Nicole Scherr, Gerd Pluschke -- Drug Discovery and Development for Leprosy / Carlos Franco-Paredes.