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Trajectories of genetics

Dujon, Bernard, 1947- author.

Trajectories of genetics

Dujon, Bernard, 1947- author.

9781119720409

9781119720393

1 online resource (223 pages) : illustrations

Biology series

Biology series (International Society for Technology in Education)

Intro -- Table of Contents -- Introduction -- 1 Following Ariadne's Thread from Genetics to DNA -- 1.1. The birth of genetics -- 1.2. The foundations of a new science -- 1.3. Gene, locus and genetic maps -- 1.4. Mutagenesis, first ideas on the material nature of the gene -- 1.5. First ideas on gene products -- 1.6. The order of things and the elements of disorder -- 1.7. Dissecting the invisible: allelism, cistron and the locus again -- 1.8. The DNA trail -- 1.9. Important ideas to remember -- 1.10. References -- 2 The Molecular Nature of Genes and Their Products

2.1. DNA and its replication -- 2.2. Permanence and alteration of DNA, mutations -- 2.3. Protein synthesis and the central dogma of molecular biology -- 2.4. The genetic code: how to read the genetic message -- 2.5. First paradigm of gene expression: the bacterial lactose operon -- 2.6. Reverse transcription and retrogenes -- 2.7. Exons, introns and splicing: the first complexity of RNA life -- 2.8. Sequence editing: the second complexity of RNA life -- 2.9. RNA interference and epigenetics -- 2.10. Important ideas to remember -- 2.11. References -- 3 Chromosomes and Reproduction

3.1. The "true" chromosomes -- 3.2. Sexual reproduction and alternating generations -- 3.3. Meiosis -- 3.4. Genetic determinism of sex -- 3.5. Clonal reproduction and its derivatives -- 3.6. The genetics of organelles -- 3.7. Important ideas to remember -- 3.8. References -- 4 From Genetic Engineering to Genomics -- 4.1. Restriction of DNA -- 4.2. Recombinant DNA and the birth of genetic engineering -- 4.3. Sequencing of biological macromolecules -- 4.4. The beginnings of genomics: the very first genome sequences -- 4.5. The trigger -- 4.6. The impact of the first real genomes

4.7. The human genome -- 4.8. New methods of genome sequencing and the current state of genomics -- 4.9. Important ideas to remember -- 4.10. References -- 5 Uniqueness and Polymorphism of Genomes -- 5.1. The immensity of nucleic acid sequences -- 5.2. Components of genomes and their replication -- 5.3. A little perspective on the content of genomes -- 5.4. Traces of the past and driving forces for the future -- 5.5. Genes in genomes -- 5.6. Genes and genetic determinism -- 5.7. Natural populations: pan-, core-genomes and SNP -- 5.8. Population genomics -- 5.9. The genetics of genomes

5.10. Important ideas to remember -- 5.11. References -- 6 Natural Dynamics and Directed Modifications of Genomes -- 6.1. The dynamics of genomes -- 6.2. Hereditary acquisitions -- 6.3. Directed manipulations of genomes: principles and tools -- 6.4. Directed manipulations of genomes: applications -- 6.5. Important ideas to remember -- 6.6. References -- 7 Of Genes and Humans -- 7.1. Ancient DNA and human history -- 7.2. Traces of the past in today's human genome -- 7.3. Traces of past climates in the trees of our forests -- 7.4. The domestication of cultivated plants 7.5. Selection of livestock

As genetics becomes increasingly important in our everyday environment, misinterpretation of its scientific foundation leads to mixed feelings of hope and fear about the potential of its applications. Trajectories of Genetics uncovers the many facets of genetics - from humans to animals, plants, and the microscopic world through more than a century of scientific progress. It summarizes the evolution of ideas as the organization and functioning of genetic material has become clearer. The book analyzes how genetic information - transmitted from generation to generation in nucleic acids - enables the fulfillment of biological functions and the evolution of the living world. It illustrates current developments in many areas: the improvement of species of agronomic interest, an increased understanding of microbial worlds, the management of genetic pathologies and the synthesis of new forms of life.

John Wiley and Sons

Genetics.

Electronic books.

Genetics

Livres numériques.

Génétique.

e-books.

Biology.

Life Sciences.

SCIENCE.

Electronic books.

Pelletier, Georges,

https://onlinelibrary.wiley.com/doi/book/10.1002/9781119720409