Process engineering emerged at the beginning of the 20th Century and has become an essential scientific discipline for the matter and energy processing industries. Its success is incontrovertible, with the exponential increase in techniques and innovations. Rapid advances in new technologies such as artificial intelligence, as well as current societal needs - sustainable development, climate change, renewable energy, the environment - are developments that must be taken into account in industrial renewal. Process Engineering Renewal 2 focuses on research in process engineering, which is partly overshadowed by the sciences that contribute to its development. The external constraints of this interface science must be seen in relation to conservation, sustainable development, global warming, etc., which are linked to current success and the difficulty of taking risks in research.