Mechanics of antigen processing. Class I MHC antigen processing / Peter J. Miller and Edward J. Collins -- The mechanics of class II processing: establichment of a peptide class II hierarchy / James R. Drake and Andrea J. Sant -- The phenomenon of immunodomination: speculations on the nature of immunodominance / Alessandro Sette and Roshni Sundaram -- Proteosome specificity and immuno-proteosomes. Endogenous antigen processing / Jonathan W. Yewdell -- Effect of the T-cell repertoire on dominance. Regulation of early T-cell development in the thymus / Thomas M. Schmitt and Juan Carlos Zuńĩga-Pfluc̈ker -- CD8 T-cell immunodominance, repertoire, and memory / Dalia E. Gaddis, Michael J. Fuller, and Allan J. Zajac -- Effects of pathogens on the immune response. Listeria monocytogenes infection and the CD8' T-cell hierarchy / Brandon B. Porter and John T. Harty -- Immunodominance in tuberculosis / david M. Lewinsohn and JoAnne L. Flynn -- T-cell specificity and respiratory virus infections / Sherry R. Crowe and David L. Woodland -- Effects of pathogens on the immune response: HIV / Masafumi Takiguchi -- The effects of pathogens on the immune system: viral hepatitis / Mala Maini and Antonio Bertoletti -- Immunodominance in the T-cell response to herpesviruses / Michael W. Munks and Ann B. Hill