chapter 1 Chemical Synthesis of Oligonucleotides: From Dream to Automation -- chapter 2 Artificial Hybridization Probes -- chapter 3 Peptide Nucleic Acid (PNA): A DNA Mimic with a Pseudopeptide Backbone -- chapter 4 Synthetic DNA Used in Amplification Reactions -- chapter 5 Artificial Nucleic Acids and Genome Profiling -- chapter 6 Site-Directed Mutagenesis -- chapter 7 Mimotopes: An Overview -- chapter 8 Artificial Genes for Chimeric Virus-Like Particles -- chapter 9 DNA Vaccines -- chapter 10 Toward Designer Diagnostic Antigens -- chapter 11 Recombinant Antibodies.