Part I: Introduction and Background. 1. Introduction. 2. Background. Part II: Literature review. 3. A Review on Error Recovery Methods with Microfluidic Biochips. Part III: Design Automation Methods. 4. Error-Correcting Sample Preparation with Cyberphysical Digital Microfluidic Lab-on-Chip. 5. Effect of Volumetric Split-Errors. 6. Error-Oblivious Sample Preparation. 7. Multi-target Sample Preparation On-demand. Part IV: Conclusions. 8. Conclusions and Future Directions. Part V: Appendix. A: Error-Correcting Sample Preparation with Cyberphysical DigitalMicrofluidic Lab-on-Chip