chapter 1 Purinergic Signaling in Osteoblasts -- chapter 2 P2 Nucleotide Receptor Signaling in Osteoclasts -- chapter 3 The Role of Purinergic Signaling in the Interactions between Skeletal Cells -- chapter 4 Role of Purine and Pyrimidine Nucleotides and Nucleosides in Regulation of Cartilage Metabolism and Chondrocyte Function -- chapter 5 ATP Release Mechanisms -- chapter 6 Purinergic Signaling in Inflammation and Immunomodulation.