chapter Section I Microbial Growth -- chapter Section II Culturing Microorganisms -- chapter Section III Bioreactor Configurations -- chapter Section IV Bioreactor Design Features -- chapter Section V Lyophilization: Growing with Biotechnology -- chapter Section VI Shear Effects in Culture -- chapter Section VII Energy Input in Bioreactors -- chapter Section VIII. Downstream Processing -- chapter Section IX Mammalian Cell Cultures -- chapter Section X Plant Cell Cultures -- chapter Section XI. Fermentation -- chapter Section XII Characteristics of Cells in Culture -- chapter Section XIII Cell Lysis -- chapter Section XIV. Cells Fractionation -- chapter Section XV Centrifugation -- chapter Section XVI Homogenization -- chapter Section XVII Refolding of Inclusion Bodies -- chapter Section XVIII Solubilization and Refolding of Proteins -- chapter Section XIX Inclusion Bodies Solubilization -- chapter Section XX Sludge Treatment -- chapter Section XXI. Freeze Drying -- chapter Section XXII Vacuum Drying -- chapter Section XXIII Diafiltration -- chapter Section XXIV. Partition Chromatographs -- chapter Section XXV Adsorption Chromatographs -- chapter Section XXVI Gel Filtration Chromatographs -- chapter Section XXVII Techniques of Genetic Engineering -- chapter Section XXVIII Industrial Biosafety.