Başlık:
Clinical and statistical considerations in personalized medicine
Yazar:
Carini, Claudio, editor.
ISBN:
9780429169335
Fiziksel Tanımlama:
1 online resource
Seri:
Chapman & Hall/CRC biostatistics series
Chapman & Hall/CRC biostatistics series (Unnumbered)
İçerik:
1. Biomarkers for drug development : the time is now! / Claudio Carini and Attila Seyhan -- 2. RNAi screens : triumphs and tribulations / Attila Seyhan and Claudio Carini -- 3. Current advances in epigenetics / Ewan Hunter and Alexandre Akoulitchev -- 4. Biomarkers and precision medicine : the case of rare diseases / Candida Fratazzi and Claudio Carini -- 5. Biomarker-informed adaptive design / Jing Wang, Mark Chang, and Sandeep Menon -- 6. Fitting the dose : adaptive staggered dose design / Joseph Wu, Sandeep Menon, and Mark Chang -- 7. Evidence-based adaptive statistical decision and design strategies for maximizing the efficiency of clinical oncology development programs with predictive biomarkers / Cong Chen and Robert A. Beckman -- 8. Biomarker identification in clinical trials / Ilya Lipkovich and Alex Dmitrienko -- 9. Multiplicity in pharmacogenomics / Lingyun Liu, Fredrick Immermann, and Sandeep Menon -- 10. Patient-reported outcomes in personalized medicine / Demissie Alemayehu and Joseph C. Cappelleri -- 11. Regulatory issues in use of biomarkers in drug development / Aloka G. Chakravarty.
Özet:
Personalized medicine has the potential to change the way we think about, identify, and manage health problems. In the pharmaceutical industry, it is already having an exciting impact on both clinical research and patient care. This impact will continue to grow as our understanding and technologies improve. With contributions from well-known industry leaders in clinical development, this book covers the practical aspects of personalized medicine, focusing on issues that have direct application in the industry. Topics include designs for targeted therapy, adaptive designs, evidence-based adaptive statistical decisions, and design strategies for maximizing the efficiency of clinical oncology-- Provided by publisher.
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Kütüphane | Materyal Türü | Demirbaş Numarası | Yer Numarası | Durumu/İade Tarihi | Materyal Ayırtma |
|---|---|---|---|---|---|
Arıyor... | E-Kitap | 540125-1001 | RM301.3 .G45 C58 2014 | Arıyor... | Arıyor... |