chapter 1 -- chapter 2 Selection of Surrogate Animal Species for Comparative Toxicogenomics -- chapter 3 Species Differences in Response to Toxic Substances: Shared Pathways of Toxicity - Value and Limitations of Omics Technologies to Elucidate Mechanism or Mode of Action -- chapter 4 Bioinformatic Approaches and Computational Models for Data Integration and Cross-Species Extrapolation in the Postgenomic Era -- chapter 5 The Extension of Molecular and Computational Information to Risk Assessment and Regulatory Decision Making*.