chapter 1 Introduction -- chapter 2 The basic model -- chapter 3 Modeling unobserved heterogeneity -- chapter 4 Modeling covariate information -- chapter 5 Alternative approaches -- chapter 6 Incorporating covariate information and unobserved hetero- geneity -- chapter 7 Working with CAMAP -- chapter 8 Estimation of odds ratio using the profile likelihood -- chapter 9 Quantification of heterogeneity in a MAIPD -- chapter 10 Scrapie in Europe: a multicountry surveillance study as a MAIPD.