chapter 1 Vascular endothelial growth factor: pathophysiology and clinical implications / chapter 2 Signal transduction of VEGF receptors toward angiogenesis / chapter 3 Growth factors and lymphangiogenesis / chapter 4 Notch and vascular development / chapter 5 Neural guidance molecules in vascular development / chapter 6 Neuropilins, receptors for the VEGF and semaphorin families, link angiogenesis and axon guidance / chapter 7 Non-angiogenic functions of VEGF / chapter 8 Contribution of pro-angiogenic hematopoietic cells to vascularization of tumor and ischemic tissue / chapter 9 Antiangiogenic drugs as broadly effective chemosensitizing agents / chapter 10 Using an anti-VEGF monoclonal antibody to treat cancer / chapter 11 Ocular neovascularization / chapter 12 Targeting VEGF for neovascular age-related macular degeneration and macular edema / chapter 13 Therapeutic angiogenesis for cardiovascular disease