Cover -- Title Page -- Copyright Page -- Contents -- Preface -- Acknowledgements -- Part 1: Fundamentals -- Chapter 1 Introduction to Genomics and Genetics -- 1.1 Introduction -- 1.2 Hub of Genomics -- 1.3 Genome Sequencing Methods -- 1.4 Variation of Genome Sequencing -- 1.5 Diseases and Disorders -- 1.6 Future Prospects -- 1.7 Conclusion -- References -- Chapter 2 An Overview of Genomics and Frontiers in Genetics for Smart Era -- 2.1 Introduction -- 2.1.1 Organization of Chapter -- 2.2 Application of Genomes-The Frontiers in Genetics -- 2.2.1 Personalized Medicine -- 2.2.2 Agriculture -- 2.2.3 Conservation Biology -- 2.2.4 Forensics -- 2.2.5 Evolutionary Studies -- 2.2.6 Biotechnology -- 2.2.7 Gene Therapy -- 2.3 Genomics in Military -- 2.3.1 Potential Career Impact Due to Genetic Variation -- 2.3.2 Challenges Remain -- 2.4 Genomics in Medicine -- 2.4.1 Cancer Genomics -- 2.4.2 Counseling in Genetics -- 2.4.3 Personalized Medicine -- 2.5 International Projects -- 2.5.1 Human Genome Project -- 2.5.2 The All of Us Research Program -- 2.5.3 The Transformation of Genomics -- 2.5.4 When All Come Together to Develop Systems Medicine -- 2.5.5 Interaction Between Genetic and Environmental Factors -- 2.6 Case Study -- 2.6.1 Target Therapies for Cancer -- 2.6.2 Pharmacogenomics and Drug Dosing -- 2.6.3 Precision Medicine in Cardiology -- 2.6.4 Personalized Treatment for Cystic Fibrosis -- 2.6.5 Diabetic Type 2 in Genomes -- 2.7 Conclusion -- References -- Chapter 3 Technical Trends in Public Healthcare and Medical Engineering -- 3.1 Introduction -- 3.2 Background Work -- 3.2.1 Recent Technologies in Healthcare and Medical Engineering -- 3.2.1.1 The Internet of Medical Things -- 3.2.1.2 Blockchain -- 3.2.1.3 Nanotechnology -- 3.2.1.4 Cloud Computing -- 3.2.1.5 Big Data and E-Health -- 3.2.1.6 Virtual Clinical Trials.

3.2.1.7 3D Printing for Healthcare and Medical Engineering -- 3.2.1.8 Telemedicine -- 3.2.2 Advancement in Healthcare and Medical Engineering -- 3.3 Current Scenario of Public Healthcare System and Medical Engineering -- 3.4 Role of AI in Healthcare -- 3.5 Technological Analysis for Healthcare System and Medical Engineering -- 3.5.1 Need of Advancement in Public Healthcare System -- 3.5.2 Advance Technology Role in Healthcare System -- 3.6 Future Aspects of AI in Healthcare and Medical Engineering -- 3.7 Conclusion -- 3.8 Future Aspect -- References -- Chapter 4 Role of Genomics in Smart Era and Its Application in COVID-19 -- 4.1 Introduction -- 4.2 Basics of Genomics -- 4.3 Evolution of Genomics -- 4.4 Characteristics of Genomics and DNA Computing -- 4.4.1 Genomics -- 4.4.2 DNA Computing -- 4.5 Types of Genomics -- 4.5.1 Structural Genomics -- 4.5.2 Function Genomics -- 4.5.3 Metagenomics -- 4.5.4 Epigenomics -- 4.6 Application Area of Genomics -- 4.7 Application of DNA Computing -- 4.8 Genomics and DNA Computing in COVID-19 Epidemic -- 4.9 Issues in Genomics and DNA Computing -- 4.10 Tools and Technology Used in Genomics Systems -- 4.11 Role of AI Technology Used in Genomics Systems -- 4.12 Related Works and Challenges -- 4.13 Future Research Dimension -- 4.14 Conclusion -- References -- Part 2: Methods and Applications -- Chapter 5 Novel Cutting-Edge Security Tools for Medical and Genomic Data With Privacy Preservation Techniques -- 5.1 Introduction -- 5.2 Background of Genomic -- 5.3 Literature Review -- 5.4 Highlights of the Proposed Methodologies -- 5.5 Results and Discussion -- 5.6 Conclusion -- References -- Chapter 6 Genomic Data Analysis With Optimized Convolutional Neural Network (CNN) for Edge Applications -- 6.1 Introduction -- 6.2 Related Work -- 6.3 Proposed Methodology -- 6.4 Conclusion -- References.

Chapter 7 Real-World Estimation of Malaria Prevalence From Genome of Vectors and Climate Analysis -- 7.1 Introduction -- 7.2 Significance of Estimation of Malaria Prevalence From Genome of Vectors and Climate Analysis -- 7.2.1 Related Work -- 7.3 Proposed Methodology -- 7.3.1 Classification Approach -- 7.3.2 Nonlinear Regression Approach -- 7.4 Conclusion -- References -- Chapter 8 Revolutionalizing Internet of Medical Things for Blockchain-Based 5G Healthcare Security and Privacy for Genomic Data -- 8.1 Introduction -- 8.1.1 Genomics Data -- 8.2 Internet of Things in Healthcare and Medical Applications (IoMT) -- 8.2.1 Benefits of IoMT -- 8.2.2 Adopting Blockchain Technology in Healthcare and Medical Applications-A General Scenario -- 8.2.3 The Cryptography Behind Blockchain -- 8.2.4 Hash Functions -- 8.2.5 Public Key Cryptography -- 8.3 Limitations of Existing Technologies in Healthcare Applications -- 8.4 Solving Healthcare Problems Using BCT -- 8.4.1 Problems in Drug Discovery -- 8.4.2 Blockchain Application to Solve Problems in Drug Discovery -- 8.4.3 Patient Data Management -- 8.4.4 Blockchain Application to Solve Patient Data Management -- 8.5 Proposed Model for 5G Healthcare -- 8.5.1 Access Security and Data Privacy -- 8.5.2 Algorithm -- 8.6 Experimental Setup and Discussion -- 8.7 Results -- 8.8 Conclusion -- References -- Chapter 9 Preserve Privacy-HD: A Privacy-Preserving Distributed Framework for Health Data -- 9.1 Introduction -- 9.1.1 Motivation -- 9.1.2 Medical Data and Interoperatability -- 9.2 Organization of Chapter -- 9.3 Related Work -- 9.4 Proposed Methodology -- 9.5 Complexity Analysis -- 9.6 Conclusion -- References -- Part 3: Future-Based Applications -- Chapter 10 Decision and Recommendation System Services for Patient Using Artificial Intelligence -- 10.1 Introduction -- 10.1.1 Effect of Internet of Medical Things Attacks.

10.1.2 Basic Structure of Defensive Plan -- 10.1.3 Security/Defense Mechanism -- 10.2 Literature Review -- 10.2.1 Healthcare Safety -- 10.2.2 Intrusion Detection -- 10.2.2.1 Types of Techniques in Intrusion Detection Systems -- 10.2.3 Anomaly Detection -- 10.2.3.1 Process of Identifying Anomalies -- 10.2.3.2 Researches on Anomaly Detection -- 10.2.3.3 Types of Anomalies -- 10.2.4 Machine Learning -- 10.3 Proposed Methodology -- 10.3.1 Pre-Processing -- 10.3.1.1 Categorization of Protocols -- 10.3.1.2 Detection Model -- 10.4 Implementation and Results Analysis -- 10.5 Results and Discussion -- 10.6 Conclusion -- References -- Chapter 11 MPHDRDNN: Meticulous Presaging of Heart Disease by Regularized DNN Through GUI -- 11.1 Introduction -- 11.2 Literature Study -- 11.3 Proposed Methodology -- 11.3.1 Proposed Flowchart of Work -- 11.4 Performance Evaluation Metrics -- 11.4.1 L1 Regularization -- 11.4.2 Implementation With L1 and L2 Reg-DNN -- 11.4.2.1 How to Implement in This Proposed Work L2 and L1 Regularization -- 11.4.2.2 Lasso Relapse -- 11.4.2.3 Edge Relapse -- 11.4.3 Graphical User System Model -- 11.5 Results and Implementation Process for Building a GUI -- 11.6 Conclusion and Future Scope -- 11.6.1 Comparative Performance Reg-DNN With Other Existing Work -- Acknowledgment -- References -- Chapter 12 Techniques for Removing Hair From Dermoscopic Images: A Survey of Current Approaches -- 12.1 Introduction -- 12.1.1 Organization of Chapter -- 12.2 Inpainting Techniques Used for Hair Removal From Dermoscopic Images -- 12.2.1 Diffusion-Based Inpainting -- 12.2.2 Texture Synthesis-Based Inpainting -- 12.2.3 Exemplar and Search-Based Inpainting -- 12.2.4 Wavelet Transform-Based Inpainting -- 12.2.5 Fast Marching Method Inpainting -- 12.2.6 Deep Learning Image Inpainting -- 12.3 Hair Removal Approaches From Dermoscopic Images.

12.3.1 Unsupervised Approaches -- 12.3.1.1 Filtering-Based Hair Removal Approaches -- 12.3.1.2 Morphological-Based Hair Removal Approaches -- 12.3.1.3 Edge-Based Hair Removal Approaches -- 12.3.2 Supervised Approaches -- 12.4 Results and Discussion -- 12.5 Conclusion -- Acknowledgment -- References -- Chapter 13 The Emergence of Blockchain Technology in Industrial Revolution 5.0 -- 13.1 Introduction -- 13.2 Literature Survey -- 13.3 Evolution of Web Technology in Association With Blockchain -- 13.3.1 Superior Security and Privacy -- 13.3.2 Gravitation Toward Cryptocurrency -- 13.3.3 Participant Providence in Industries by Web 3.0 -- 13.3.3.1 Currency Exchange Procedures -- 13.3.3.2 Social Media and Messaging Platforms -- 13.3.3.3 Browsers -- 13.3.3.4 Banking and Finance Industries -- 13.4 Understanding of Basic Key Terminologies -- 13.4.1 Distributed Ledger Technology -- 13.4.2 Mining -- 13.4.3 Consensus Mechanisms and Protocols -- 13.4.3.1 Double Spending Problem -- 13.4.3.2 Byzantine General Problem -- 13.5 Industrial Components Associated With Blockchain -- 13.5.1 Cryptocurrency -- 13.5.2 Decentralized Applications (DApps) -- 13.5.3 Smart Contracts -- 13.6 Contribution of Blockchain for Revolutionizing Industrial Aspects -- 13.6.1 Introducing the Ethereum Network -- 13.6.1.1 Ethereum Virtual Machine -- 13.6.1.2 Cloud Computing -- 13.6.2 Implementation of Blockchain for Enhancing Security and Privacy -- 13.6.3 Development of Token Economy Based on Cryptocurrency -- 13.6.4 Developing the Market for Smart Real Estate -- 13.6.4.1 Platforms and Marketplaces -- 13.6.4.2 No Intermediaries -- 13.6.4.3 Illiquid Characteristics of Real Estate -- 13.6.4.4 Fractional Ownership of Real Estate -- 13.6.4.5 Decentralization -- 13.6.4.6 Costs -- 13.6.5 Development of Supply Chain Management Systems Based on Distributed Ledgers.