DNA nanotechnology for cell research : from bioanalysis to biomedicine için kapak resmi
Başlık:
DNA nanotechnology for cell research : from bioanalysis to biomedicine
Yazar:
Nie, Zhou, editor.
ISBN:
9783527840793

9783527840809

9783527840816
Fiziksel Tanımlama:
1 online resource : illustrations (some color)
İçerik:
Developing DNA aptamer toolbox for cell research -- Bacterial detection with functional nucleic acids Escherichia coli as a case study -- From ligand-binding aptamers to molecular switches -- DNA nanotechnology-based microfluidics for liquid biopsy -- Spatiotemporal-controlled cell membrane engineering using DNS nanotechnology -- Metal-dependent DNAzymes for cell surface engineering and intracellular bioimaging -- DNA nanomotors for bioimaging in living cells -- Illuminating RNA in live cells with inorganic nanoparticles-based DNA sensor tenchnology -- Building DNA computing system for smart biosensing and clinical diagnosis -- Intelligent sense-on-demand DNA circuits for amplified bioimaging in living cells -- DNA nanoscaffolds for biomacromolecules organization and bioimaging applications -- Adopting nucleic acid nantechnology for genetic regulation in vivo -- Cell membrane functionalization via nucleic acid tools for visualization and regulation of cellular receptors -- Harnessing DNA nanotechnology for nongenetic manipulation and functionalization of cell surface receptor -- DNA-based cell surface engineering for programming multiple cell-cell interactions -- Designer DNA nanostructures and their cellular uptake behaviors -- Toward production of nucleic acid nanostructures in life cells and their biomedical applications -- Engineering nucleic acid structures for programmable intracellular biocomputation -- DNA supramolecular hydrogels for biomedical applications -- Rolling circle amplification-based DNA nanotechnology for cell research -- Precise integration of therapeutics in DNA-based nanomaterials for cancer treatments.
Özet:
"DNA Nanotechnology for Cell Research Comprehensive coverage of DNA nanotechnology with a focus on its biomedical applications in disease diagnosis, gene therapy, and drug delivery Bringing together multidisciplinary aspects of chemical, material, and biological engineering, DNA Nanotechnology for Cell Research: From Bioanalysis to Biomedicine presents an overview of DNA nanotechnology with emphasis on a variety of different applications in cell research and engineering, covering a unique collection of DNA nanotechnology for fundamental research and engineering of living cells, mostly in cellulo and in vivo, for the first time. Broad coverage of this book ranges from pioneering concepts of DNA nanotechnology to cutting-edge reports regarding the use of DNA nanotechnology for fundamental cell science and related biomedical engineering applications in sensing, bioimaging, cell manipulation, gene therapy, and drug delivery. The text is divided into four parts. Part I surveys the progress of functional DNA nanotechnology tools for cellular recognition. Part II illustrates the use of DNA-based biochemical sensors to monitor and image intracellular molecules and processes. Part III examines the use of DNA to regulate biological functions of individual cells. Part IV elucidates the use of DNA nanotechnology for cell-targeted medical applications. Sample topics covered in DNA Nanotechnology for Cell Research include: Selections and applications of functional nucleic acid toolkits, including DNA/RNA aptamers, DNAzymes, and riboswitches, for cellular recognition, metabolite detection, and liquid biopsy. Developing intelligent DNA nanodevices implemented in living cells for amplified cell imaging, smart intracellular sensing, and in cellulo programmable biocomputing. Harnessing dynamic DNA nanotechnology for non-genetic cell membrane engineering, receptor signaling reprogramming, and cellular behavior regulation. Construction of biocompatible nucleic acid nanostructures as precisely controlled vehicles for drug delivery, immunotherapy, and tissue engineering. Providing an up-to-date tutorial style overview along with a highly valuable in-depth perspective, DNA Nanotechnology for Cell Research is an essential resource for the entire DNA-based nanotechnology community, including analytical chemists, biochemists, materials scientists, and bioengineers."-- Provided by publisher
Notlar:
John Wiley and Sons
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