This book constitutes the post-conference proceedings of the First International Conference on Advanced Computational Applications of Geometric Algebra, ICACGA 2022, held in Denver, CO, USA, during October 2-5, 2022. The 18 full papers presented in this book together with 12 abstracts of invited talks were carefully reviewed and selected from 24 submissions. The papers are grouped in the following topical sections: geometric applications; computer science applications; technological applications; and applications to physics and mathematics.