This book explains and discusses in simple language the structure and function of botulinum toxin and other neurotoxins as well as the rational for its utility in different disease conditions. Safety, factors affecting efficacy and duration of action, as well as cost and insurance issues are also addressed. Updates to the new edition include information on new indications, new approvals by FDA, new positive information on childhood indications, as well as data on long-term use of botulinum toxins therapy in several medical ailments (particularly migraine) that demonstrate its safety when applied properly and according to the published guidelines, are all included. In addition, two new chapters cover botulinum toxin therapy in dentistry and in veterinary medicine.