This book constitutes the proceedings of the 19th International Conference on Design Science Research in Information Systems and Technology, DESRIST 2024, which was held in Trollhättan, Sweden, during June 3-5, 2024. The 30 full papers presented in this book were carefully reviewed and selected from 69 submissions. The papers are divided into the following topical sections: DSR for a resilient world (theme track); general track; DSR methods and education; DSR in practice; and emerging topics in DSR.