This book highlights recent research on intelligent systems and nature-inspired computing. It presents 47 selected papers focused on Smart Healthcare from the 23rd International Conference on Intelligent Systems Design and Applications (ISDA 2023), which was held in 5 different cities namely Olten, Switzerland; Porto, Portugal; Kaunas, Lithuania; Greater Noida, India; Kochi, India, and in online mode. The ISDA is a premier conference in the field of artificial intelligence, and the latest installment brought together researchers, engineers, and practitioners whose work involves intelligent systems and their applications in industry. ISDA 2023 had contributions by authors from 64 countries. This book offers a valuable reference guide for all medical doctors, scientists, academicians, researchers, students, and practitioners in the field of artificial intelligence and smart health care.