This book constitutes the refereed proceedings of the 6th IFIP TC 12 International Conference on Intelligence Science, ICIS 2024, held in Nanjing, China, in October 25-28, 2024. The 23 full papers and 2 short papers presented here were carefully reviewed and selected from 32 submissions. These papers have been categorized into the following sections: Machine Learning; Causal Reasoning; Large Language Model; Intelligent Robot; Perceptual Intelligence; AI for Science; Medical Artificial Intelligence.