This book constitutes the proceedings of the 2nd International Conference on Data Security and Privacy Protection, DSPP 2024, held in Xi'an, China, during October 25-28, 2024. The 34 full papers included in this volume were carefully reviewed and selected from a total of 99 submissions. The DSPP 2024 conference promotes and stimulates discussion on the latest theories, algorithms, applications, and emerging topics on data security and privacy protection. It encourages the cross-fertilization of ideas and provides a platform for researchers, professionals, and students worldwide to discuss and present their research results.