This book constitutes the proceedings of the 43rd International Conference on Conceptual Modeling, ER 2024, which took place in Pittsburgh, PA, USA, during October 28-31, 2024. The 22 full papers presented in this volume were carefully reviewed and selected from 113 submissions. They are grouped into the following topics: process modeling; advanced modeling languages; ontological modeling; domain and goal modeling; language models and conceptual modeling; applications of conceptual modeling.