This book constitutes the refereed proceedings of the First Conference on Blockchain and Web3 Technology Innovation and Application, BWTAC 2024, held in Guangzhou, China, during, November 6-8, 2024. The 36 full papers and 9 short papers included in this book were carefully reviewed and selected from 106 submissions. They were categorized in the following topica sections: Architectures and Technologies, Privacy Protection and Data Security, Artificial Intelligences, Security, Trading Systems, Cross Domains Applications and Emerging Technologies.